Weight variation before and after surgery in Parkinson's disease: a noradrenergic modulation?
Identifieur interne : 000B53 ( Main/Exploration ); précédent : 000B52; suivant : 000B54Weight variation before and after surgery in Parkinson's disease: a noradrenergic modulation?
Auteurs : Joana Guimarães [Portugal] ; Eduardo Moura ; Maria Augusta Vieira-Coelho ; Carolina GarrettSource :
- Movement disorders : official journal of the Movement Disorder Society [ 1531-8257 ] ; 2012.
English descriptors
- KwdEn :
- Body Weight (physiology), Deep Brain Stimulation, Humans, Hypothalamus (physiopathology), Locus Coeruleus (physiopathology), Norepinephrine (physiology), Parkinson Disease (surgery), Subthalamic Nucleus (physiopathology), Subthalamic Nucleus (surgery), Sympathetic Nervous System (physiopathology), Weight Loss.
- MESH :
- chemical , physiology : Norepinephrine.
- physiology : Body Weight.
- physiopathology : Hypothalamus, Locus Coeruleus, Subthalamic Nucleus, Sympathetic Nervous System.
- surgery : Parkinson Disease, Subthalamic Nucleus.
- Deep Brain Stimulation, Humans, Weight Loss.
Abstract
Changes in the nutritional profile of patients with Parkinson's disease have been reported before and after deep brain stimulation surgery. The major determinants of the weight variation in Parkinson's disease are not yet understood, and the mechanism seems complex. Based on the influence of the sympathetic nervous system in metabolic syndrome obesity, the intent of the present review is to consider the role of noradrenergic modulation on weight variations in Parkinson's disease. In this review the authors raise the following hypothesis: weight variation in Parkinson's disease before and after deep brain stimulation of the subthalamic nucleus could be influenced by noradrenergic interaction between the locus coeruleus, subthalamic nucleus, and hypothalamic nucleus.
DOI: 10.1002/mds.25063
PubMed: 22700383
Affiliations:
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Le document en format XML
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The major determinants of the weight variation in Parkinson's disease are not yet understood, and the mechanism seems complex. Based on the influence of the sympathetic nervous system in metabolic syndrome obesity, the intent of the present review is to consider the role of noradrenergic modulation on weight variations in Parkinson's disease. In this review the authors raise the following hypothesis: weight variation in Parkinson's disease before and after deep brain stimulation of the subthalamic nucleus could be influenced by noradrenergic interaction between the locus coeruleus, subthalamic nucleus, and hypothalamic nucleus.</div></front></TEI><affiliations><list><country><li>Portugal</li></country></list><tree><noCountry><name sortKey="Garrett, Carolina" sort="Garrett, Carolina" uniqKey="Garrett C" first="Carolina" last="Garrett">Carolina Garrett</name><name sortKey="Moura, Eduardo" sort="Moura, Eduardo" uniqKey="Moura E" first="Eduardo" last="Moura">Eduardo Moura</name><name sortKey="Vieira Coelho, Maria Augusta" sort="Vieira Coelho, Maria Augusta" uniqKey="Vieira Coelho M" first="Maria Augusta" last="Vieira-Coelho">Maria Augusta Vieira-Coelho</name></noCountry><country name="Portugal"><noRegion><name sortKey="Guimaraes, Joana" sort="Guimaraes, Joana" uniqKey="Guimaraes J" first="Joana" last="Guimarães">Joana Guimarães</name></noRegion></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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